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OT - a shot in the arm

BP
Bob Pdml
Thu, Mar 4, 2021 6:07 PM

Why would you choose one (type of) vaccine over another, given that they all seem more or less equally effective, have no serious side-effects, and mostly all require two doses?

On 4 Mar 2021, at 17:19, mike wilson m.9.wilson@ntlworld.com wrote:

Excellent stuff!  I was spiked about three weeks ago.  Knocked me on my backside for a couple of days but wore off very quickly.  Mine was Astra-Zeneca (no choice; I would have preferred the mRNA type to the viral vector one) which is supposed to be intramuscular.  If that's how it was administered, it was the most painless IM injection I've ever had - in fact, the most painless injection full stop.

Why would you choose one (type of) vaccine over another, given that they all seem more or less equally effective, have no serious side-effects, and mostly all require two doses? > On 4 Mar 2021, at 17:19, mike wilson <m.9.wilson@ntlworld.com> wrote: > > Excellent stuff! I was spiked about three weeks ago. Knocked me on my backside for a couple of days but wore off very quickly. Mine was Astra-Zeneca (no choice; I would have preferred the mRNA type to the viral vector one) which is supposed to be intramuscular. If that's how it was administered, it was the most painless IM injection I've ever had - in fact, the most painless injection full stop. >>
MW
mike wilson
Thu, Mar 4, 2021 6:41 PM

The mRNA types produce two types of immunity.  One that is present in bodily fluids, such as blood.  This is the type that produces antibodies and is the way that historical vaccines work.  mRNA vaccines also trigger cellular immunity, whereby production of phagocytes removes virus-infected cells.  Arguably there's a third way, the stimulation of cells to produce substances called cytokines which play a part in the way other cells are involved in immune response.  Plus it's new technology and I'm interested.

On 04 March 2021 at 18:07 Bob Pdml pdmlbw@gmail.com wrote:

Why would you choose one (type of) vaccine over another, given that they all seem more or less equally effective, have no serious side-effects, and mostly all require two doses?

On 4 Mar 2021, at 17:19, mike wilson m.9.wilson@ntlworld.com wrote:

Excellent stuff!  I was spiked about three weeks ago.  Knocked me on my backside for a couple of days but wore off very quickly.  Mine was Astra-Zeneca (no choice; I would have preferred the mRNA type to the viral vector one) which is supposed to be intramuscular.  If that's how it was administered, it was the most painless IM injection I've ever had - in fact, the most painless injection full stop.

--
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The mRNA types produce two types of immunity. One that is present in bodily fluids, such as blood. This is the type that produces antibodies and is the way that historical vaccines work. mRNA vaccines also trigger cellular immunity, whereby production of phagocytes removes virus-infected cells. Arguably there's a third way, the stimulation of cells to produce substances called cytokines which play a part in the way other cells are involved in immune response. Plus it's new technology and I'm interested. > On 04 March 2021 at 18:07 Bob Pdml <pdmlbw@gmail.com> wrote: > > > Why would you choose one (type of) vaccine over another, given that they all seem more or less equally effective, have no serious side-effects, and mostly all require two doses? > > > On 4 Mar 2021, at 17:19, mike wilson <m.9.wilson@ntlworld.com> wrote: > > > > Excellent stuff! I was spiked about three weeks ago. Knocked me on my backside for a couple of days but wore off very quickly. Mine was Astra-Zeneca (no choice; I would have preferred the mRNA type to the viral vector one) which is supposed to be intramuscular. If that's how it was administered, it was the most painless IM injection I've ever had - in fact, the most painless injection full stop. > >> > -- > %(real_name)s Pentax-Discuss Mail List > To unsubscribe send an email to pdml-leave@pdml.net > to UNSUBSCRIBE from the PDML, please visit the link directly above and follow the directions.
J
John
Thu, Mar 4, 2021 7:29 PM

My mom was an RN. One of the pieces of "art" she had on the wall at home was a
photo of a Chimpanzee in a nurses hat with the caption:

"One more word out of you and you're getting the SQUARE NEEDLE!"

On 3/4/2021 12:19:09, mike wilson wrote:

Excellent stuff!  I was spiked about three weeks ago.  Knocked me on my
backside for a couple of days but wore off very quickly.  Mine was
Astra-Zeneca (no choice; I would have preferred the mRNA type to the viral
vector one) which is supposed to be intramuscular.  If that's how it was
administered, it was the most painless IM injection I've ever had - in fact,
the most painless injection full stop.

On 04 March 2021 at 16:54 ann sanfedele annsan@nyc.rr.com wrote:

Those of you who are on FB know this already..

I got my first dose of the Pfizer vaccine on Monday...  arm achy after a
few hours and quite sleepy for a day or two but no serious side effects and
did wonders for my spirit.

--

--
Science - Questions we may never find answers for.
Religion - Answers we must never question.

My mom was an RN. One of the pieces of "art" she had on the wall at home was a photo of a Chimpanzee in a nurses hat with the caption: "One more word out of you and you're getting the SQUARE NEEDLE!" On 3/4/2021 12:19:09, mike wilson wrote: > Excellent stuff! I was spiked about three weeks ago. Knocked me on my > backside for a couple of days but wore off very quickly. Mine was > Astra-Zeneca (no choice; I would have preferred the mRNA type to the viral > vector one) which is supposed to be intramuscular. If that's how it was > administered, it was the most painless IM injection I've ever had - in fact, > the most painless injection full stop. >> On 04 March 2021 at 16:54 ann sanfedele <annsan@nyc.rr.com> wrote: >> >> >> Those of you who are on FB know this already.. >> >> I got my first dose of the Pfizer vaccine on Monday... arm achy after a >> few hours and quite sleepy for a day or two but no serious side effects and >> did wonders for my spirit. > -- -- Science - Questions we may never find answers for. Religion - Answers we must never question.
RR
Ralf R Radermacher
Thu, Mar 4, 2021 7:31 PM

Am 04.03.21 um 17:54 schrieb ann sanfedele:

I got my first dose of the Pfizer vaccine on Monday...

Good to know. My turn will be some time in early summer at best and
Michael's probably in late summer. Not holding our breath yet, except
when we're outside...

As a matter of fact I haven't left the house since Xmas. Nowhere to go.
Michael does the week's shopping on Tuesday mornings and that's all our
physical contact to the outside world.

Given that we've been working at home for the last 40 years, home office
is nothing new for us.

The only real nuisance is that going to Dunkirk is totally out of the
question as they have an incidence of 900 per 100,000, most of it with
the British variant, and they're facing a few more weekends in total
lockdown.

Business has been quite a rollercoaster for the last 12 months but
overall still enough to be on the positive side, so we're not
complaining. Keeping our fingers crossed that it will stay this way.

Ralf

--
Ralf R. Radermacher  -  Köln/Cologne, Germany
Blog  : http://the-real-fotoralf.blogspot.com
Audio : http://aporee.org/maps/projects/fotoralf
Web  : http://www.fotoralf.de

Am 04.03.21 um 17:54 schrieb ann sanfedele: > I got my first dose of the Pfizer vaccine on Monday... Good to know. My turn will be some time in early summer at best and Michael's probably in late summer. Not holding our breath yet, except when we're outside... As a matter of fact I haven't left the house since Xmas. Nowhere to go. Michael does the week's shopping on Tuesday mornings and that's all our physical contact to the outside world. Given that we've been working at home for the last 40 years, home office is nothing new for us. The only real nuisance is that going to Dunkirk is totally out of the question as they have an incidence of 900 per 100,000, most of it with the British variant, and they're facing a few more weekends in total lockdown. Business has been quite a rollercoaster for the last 12 months but overall still enough to be on the positive side, so we're not complaining. Keeping our fingers crossed that it will stay this way. Ralf -- Ralf R. Radermacher - Köln/Cologne, Germany Blog : http://the-real-fotoralf.blogspot.com Audio : http://aporee.org/maps/projects/fotoralf Web : http://www.fotoralf.de
HT
Henk Terhell
Thu, Mar 4, 2021 7:32 PM

Ann, that is positive news for  negative testing!
We were starting rather late here with the vaccination.
Perhaps I get my first shot before the end of this month, possibly
before the  EU approves the Sputnik vaccin!

Henk

Op 2021-03-04 om 17:54 schreef ann sanfedele:

Those of you who are on FB know this already..

I got my first dose of the Pfizer vaccine on Monday...  arm achy after
a few hours and quite sleepy for a day or two but no serious side effects
and did wonders for my spirit.

ann

Ann, that is positive news for  negative testing! We were starting rather late here with the vaccination. Perhaps I get my first shot before the end of this month, possibly before the  EU approves the Sputnik vaccin! Henk Op 2021-03-04 om 17:54 schreef ann sanfedele: > Those of you who are on FB know this already.. > > I got my first dose of the Pfizer vaccine on Monday...  arm achy after > a few hours and quite sleepy for a day or two but no serious side effects > and did wonders for my spirit. > > ann >
J
John
Thu, Mar 4, 2021 7:42 PM

Wasn't "cytokine storm" what made the second wave of Spanish Flu so deadly?

On 3/4/2021 13:41:08, mike wilson wrote:

The mRNA types produce two types of immunity.  One that is present in bodily
fluids, such as blood.  This is the type that produces antibodies and is the
way that historical vaccines work.  mRNA vaccines also trigger cellular
immunity, whereby production of phagocytes removes virus-infected cells.
Arguably there's a third way, the stimulation of cells to produce substances
called cytokines which play a part in the way other cells are involved in
immune response.  Plus it's new technology and I'm interested.

On 04 March 2021 at 18:07 Bob Pdml pdmlbw@gmail.com wrote:

Why would you choose one (type of) vaccine over another, given that they
all seem more or less equally effective, have no serious side-effects, and
mostly all require two doses?

On 4 Mar 2021, at 17:19, mike wilson m.9.wilson@ntlworld.com wrote:

Excellent stuff!  I was spiked about three weeks ago.  Knocked me on my
backside for a couple of days but wore off very quickly.  Mine was
Astra-Zeneca (no choice; I would have preferred the mRNA type to the
viral vector one) which is supposed to be intramuscular.  If that's how
it was administered, it was the most painless IM injection I've ever had

  • in fact, the most painless injection full stop.

--

--
Science - Questions we may never find answers for.
Religion - Answers we must never question.

Wasn't "cytokine storm" what made the second wave of Spanish Flu so deadly? On 3/4/2021 13:41:08, mike wilson wrote: > The mRNA types produce two types of immunity. One that is present in bodily > fluids, such as blood. This is the type that produces antibodies and is the > way that historical vaccines work. mRNA vaccines also trigger cellular > immunity, whereby production of phagocytes removes virus-infected cells. > Arguably there's a third way, the stimulation of cells to produce substances > called cytokines which play a part in the way other cells are involved in > immune response. Plus it's new technology and I'm interested. > >> On 04 March 2021 at 18:07 Bob Pdml <pdmlbw@gmail.com> wrote: >> >> >> Why would you choose one (type of) vaccine over another, given that they >> all seem more or less equally effective, have no serious side-effects, and >> mostly all require two doses? >> >>> On 4 Mar 2021, at 17:19, mike wilson <m.9.wilson@ntlworld.com> wrote: >>> >>> Excellent stuff! I was spiked about three weeks ago. Knocked me on my >>> backside for a couple of days but wore off very quickly. Mine was >>> Astra-Zeneca (no choice; I would have preferred the mRNA type to the >>> viral vector one) which is supposed to be intramuscular. If that's how >>> it was administered, it was the most painless IM injection I've ever had >>> - in fact, the most painless injection full stop. >>>> >> -- -- Science - Questions we may never find answers for. Religion - Answers we must never question.
J
John
Thu, Mar 4, 2021 7:50 PM

Maybe you'll just grow "flaming locks of auburn hair".

On 3/4/2021 12:32:01, Daniel J. Matyola wrote:

Wonderful, Ann.

We are scheduled for our second dose of the Dolly Parton vaccine on St
Patrick's day.
I wonder if I will turn green or grow breasts.

Dan Matyola
https://tinyurl.com/DJM-Pentax-Gallery
https://tinyurl.com/DJM-Pentax-Gallery

On Thu, Mar 4, 2021 at 11:54 AM ann sanfedele annsan@nyc.rr.com wrote:

Those of you who are on FB know this already..

I got my first dose of the Pfizer vaccine on Monday...  arm achy after a
few hours and quite sleepy for a day or two but no serious side effects
and did wonders for my spirit.

ann

--
ann sanfedele photography
https://annsan.smugmug.com
https://www.cafepress.com/+ann-sanfedele+gifts
https://www.lulu.com/spotlight/annsan
https://www.createphotocalendars.com/Shop/annsanfedelecalendarsandbooks

--
Science - Questions we may never find answers for.
Religion - Answers we must never question.

Maybe you'll just grow "flaming locks of auburn hair". On 3/4/2021 12:32:01, Daniel J. Matyola wrote: > Wonderful, Ann. > > We are scheduled for our second dose of the Dolly Parton vaccine on St > Patrick's day. > I wonder if I will turn green or grow breasts. > > Dan Matyola > *https://tinyurl.com/DJM-Pentax-Gallery > <https://tinyurl.com/DJM-Pentax-Gallery>* > > > > On Thu, Mar 4, 2021 at 11:54 AM ann sanfedele <annsan@nyc.rr.com> wrote: > >> Those of you who are on FB know this already.. >> >> I got my first dose of the Pfizer vaccine on Monday... arm achy after a >> few hours and quite sleepy for a day or two but no serious side effects >> and did wonders for my spirit. >> >> ann >> >> -- >> ann sanfedele photography >> https://annsan.smugmug.com >> https://www.cafepress.com/+ann-sanfedele+gifts >> https://www.lulu.com/spotlight/annsan >> https://www.createphotocalendars.com/Shop/annsanfedelecalendarsandbooks -- Science - Questions we may never find answers for. Religion - Answers we must never question.
DJ
Daniel J. Matyola
Thu, Mar 4, 2021 7:56 PM

My favorite Solly Quote (to Johnny Carson):  "It costs a lot of money to
look this cheap."

Dan Matyola
https://tinyurl.com/DJM-Pentax-Gallery
https://tinyurl.com/DJM-Pentax-Gallery

On Thu, Mar 4, 2021 at 2:50 PM John jsessoms002@nc.rr.com wrote:

Maybe you'll just grow "flaming locks of auburn hair".

On 3/4/2021 12:32:01, Daniel J. Matyola wrote:

Wonderful, Ann.

We are scheduled for our second dose of the Dolly Parton vaccine on St
Patrick's day.
I wonder if I will turn green or grow breasts.

Dan Matyola
https://tinyurl.com/DJM-Pentax-Gallery
https://tinyurl.com/DJM-Pentax-Gallery

On Thu, Mar 4, 2021 at 11:54 AM ann sanfedele annsan@nyc.rr.com wrote:

Those of you who are on FB know this already..

I got my first dose of the Pfizer vaccine on Monday...  arm achy after a
few hours and quite sleepy for a day or two but no serious side effects
and did wonders for my spirit.

ann

--
ann sanfedele photography
https://annsan.smugmug.com
https://www.cafepress.com/+ann-sanfedele+gifts
https://www.lulu.com/spotlight/annsan
https://www.createphotocalendars.com/Shop/annsanfedelecalendarsandbooks

--
Science - Questions we may never find answers for.
Religion - Answers we must never question.

%(real_name)s Pentax-Discuss Mail List
To unsubscribe send an email to pdml-leave@pdml.net
to UNSUBSCRIBE from the PDML, please visit the link directly above and
follow the directions.

My favorite Solly Quote (to Johnny Carson): "It costs a lot of money to look this cheap." Dan Matyola *https://tinyurl.com/DJM-Pentax-Gallery <https://tinyurl.com/DJM-Pentax-Gallery>* On Thu, Mar 4, 2021 at 2:50 PM John <jsessoms002@nc.rr.com> wrote: > Maybe you'll just grow "flaming locks of auburn hair". > > On 3/4/2021 12:32:01, Daniel J. Matyola wrote: > > Wonderful, Ann. > > > > We are scheduled for our second dose of the Dolly Parton vaccine on St > > Patrick's day. > > I wonder if I will turn green or grow breasts. > > > > Dan Matyola > > *https://tinyurl.com/DJM-Pentax-Gallery > > <https://tinyurl.com/DJM-Pentax-Gallery>* > > > > > > > > On Thu, Mar 4, 2021 at 11:54 AM ann sanfedele <annsan@nyc.rr.com> wrote: > > > >> Those of you who are on FB know this already.. > >> > >> I got my first dose of the Pfizer vaccine on Monday... arm achy after a > >> few hours and quite sleepy for a day or two but no serious side effects > >> and did wonders for my spirit. > >> > >> ann > >> > >> -- > >> ann sanfedele photography > >> https://annsan.smugmug.com > >> https://www.cafepress.com/+ann-sanfedele+gifts > >> https://www.lulu.com/spotlight/annsan > >> https://www.createphotocalendars.com/Shop/annsanfedelecalendarsandbooks > > > > -- > Science - Questions we may never find answers for. > Religion - Answers we must never question. > -- > %(real_name)s Pentax-Discuss Mail List > To unsubscribe send an email to pdml-leave@pdml.net > to UNSUBSCRIBE from the PDML, please visit the link directly above and > follow the directions. >
MW
mike wilson
Thu, Mar 4, 2021 8:35 PM

That and Bradykinin 'storms' seem to be the causes of the major reactions to Covid.  Research is ongoing as to why some individuals overreact in the production of these substances, whose normal function is to cause inflammation and therefore immobilisation of injured parts.

On 04 March 2021 at 19:42 John jsessoms002@nc.rr.com wrote:

Wasn't "cytokine storm" what made the second wave of Spanish Flu so deadly?

On 3/4/2021 13:41:08, mike wilson wrote:

The mRNA types produce two types of immunity.  One that is present in bodily
fluids, such as blood.  This is the type that produces antibodies and is the
way that historical vaccines work.  mRNA vaccines also trigger cellular
immunity, whereby production of phagocytes removes virus-infected cells.
Arguably there's a third way, the stimulation of cells to produce substances
called cytokines which play a part in the way other cells are involved in
immune response.  Plus it's new technology and I'm interested.

On 04 March 2021 at 18:07 Bob Pdml pdmlbw@gmail.com wrote:

Why would you choose one (type of) vaccine over another, given that they
all seem more or less equally effective, have no serious side-effects, and
mostly all require two doses?

On 4 Mar 2021, at 17:19, mike wilson m.9.wilson@ntlworld.com wrote:

Excellent stuff!  I was spiked about three weeks ago.  Knocked me on my
backside for a couple of days but wore off very quickly.  Mine was
Astra-Zeneca (no choice; I would have preferred the mRNA type to the
viral vector one) which is supposed to be intramuscular.  If that's how
it was administered, it was the most painless IM injection I've ever had

  • in fact, the most painless injection full stop.
That and Bradykinin 'storms' seem to be the causes of the major reactions to Covid. Research is ongoing as to why some individuals overreact in the production of these substances, whose normal function is to cause inflammation and therefore immobilisation of injured parts. > On 04 March 2021 at 19:42 John <jsessoms002@nc.rr.com> wrote: > > > Wasn't "cytokine storm" what made the second wave of Spanish Flu so deadly? > > On 3/4/2021 13:41:08, mike wilson wrote: > > The mRNA types produce two types of immunity. One that is present in bodily > > fluids, such as blood. This is the type that produces antibodies and is the > > way that historical vaccines work. mRNA vaccines also trigger cellular > > immunity, whereby production of phagocytes removes virus-infected cells. > > Arguably there's a third way, the stimulation of cells to produce substances > > called cytokines which play a part in the way other cells are involved in > > immune response. Plus it's new technology and I'm interested. > > > >> On 04 March 2021 at 18:07 Bob Pdml <pdmlbw@gmail.com> wrote: > >> > >> > >> Why would you choose one (type of) vaccine over another, given that they > >> all seem more or less equally effective, have no serious side-effects, and > >> mostly all require two doses? > >> > >>> On 4 Mar 2021, at 17:19, mike wilson <m.9.wilson@ntlworld.com> wrote: > >>> > >>> Excellent stuff! I was spiked about three weeks ago. Knocked me on my > >>> backside for a couple of days but wore off very quickly. Mine was > >>> Astra-Zeneca (no choice; I would have preferred the mRNA type to the > >>> viral vector one) which is supposed to be intramuscular. If that's how > >>> it was administered, it was the most painless IM injection I've ever had > >>> - in fact, the most painless injection full stop.
B
Bill
Thu, Mar 4, 2021 9:06 PM

On Thu., Mar. 4, 2021, 1:42 p.m. John, jsessoms002@nc.rr.com wrote:

Wasn't "cytokine storm" what made the second wave of Spanish Flu so deadly?

Interesting bit of trivia, the Spanish flu should rightly have been called
the Kansas flu as that is where it came from.

bill

On Thu., Mar. 4, 2021, 1:42 p.m. John, <jsessoms002@nc.rr.com> wrote: > Wasn't "cytokine storm" what made the second wave of Spanish Flu so deadly? > Interesting bit of trivia, the Spanish flu should rightly have been called the Kansas flu as that is where it came from. bill >